Cajal Bodies and Histone Locus Bodies in Drosophila and Xenopus
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چکیده
منابع مشابه
Myc Localizes to Histone Locus Bodies during Replication in Drosophila
Myc is an important protein at the center of multiple pathways required for growth and proliferation in animals. The absence of Myc is lethal in flies and mice, and its over-production is a potent inducer of over-proliferation and cancer. Myc protein is localized to the nucleus where it executes its many functions, however the specific sub-nuclear localization of Myc has rarely been reported. T...
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What are they? Cajal bodies are nuclear suborganelles, typically 0.5 μm in diameter, discovered in 1903 by Santiago Ramón y Cajal. They are dynamic structures involved in the biogenesis of small ribonucleoproteins (RNPs). Cajal bodies contain the highest concentration of small RNPs in the nucleoplasm, as well as a host of other protein factors involved in diverse processes. They are not major s...
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A dystroglycan ligand in the brain ystroglycans are present on the surfaces of cells throughout the body, anchoring cells in the matrix that surrounds them. This function is conspicuously important for muscle cells. Defects in the protein dystrophin, which is D connected to dystroglycan, destabilize the connection of muscle cells to their matrix and cause muscular dystrophy. Dystroglycans are a...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Symposia on Quantitative Biology
سال: 2010
ISSN: 0091-7451,1943-4456
DOI: 10.1101/sqb.2010.75.005